Prefix with sphere

This time we are looking on the crossword puzzle clue for: Prefix with sphere.
it’s A 18 letters crossword definition.
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Possible Answers:

IONO-.

Last seen on: –LA Times Crossword 26 May 21, Wednesday
LA Times Crossword 5 Jan 21, Tuesday
LA Times Crossword 1 Oct 19, Tuesday
NY Times Crossword 30 Jul 19, Tuesday
LA Times Crossword 22 Jul 19, Monday